Geoff is the founding director of the Center for Applied Genomics & Precision Medicine at the Duke University Medical Center. He is also the founding director of MEDx, a partnership between the Schools of Medicine and Engineering created to spark and translate innovation. He is a professor of Medicine, Pathology, and Biomedical Engineering at Duke University.

Geoff has pioneered translational genomics, the development of novel diagnostics, and precision medicine, initiating programs in genome enabled biomarker discovery, longitudinal registries with linked molecular and clinical data, biomarker-informed clinical trials, and the development of novel practice models and implementation research for the integration of genomic tools and digital health technologies into heath care delivery systems. He has over 200 published papers, and funding from NIH, DOD, Air Force, DARPA, the Gates Foundation, and industry. He has received a number of awards for his research accomplishments, including the Innovator in Medicine Award from Millennium Pharmaceuticals and the Basic Research Achievement Award in Cardiovascular Medicine from Duke. In 2015, he was an honored speaker at the White House Champions for Change in Precision Medicine. He is a founding member and former board member of the Personalized Medicine Coalition, a senior consulting editor for The Journal of the American College of Cardiology, and an editorial advisor for Science Translational Medicine. He is also the editor of Genomic and Personalized Medicine (Elsevier).

Geoff has been a member of the Pappas Ventures Scientific Advisory Board since 2007.


Boston University (MD)
Boston University (PhD in Biophysics)
Beth Israel Hospital (Internal Medicine Residency)