LEAD Therapeutics, Inc., a chemistry-driven drug discovery company, today announced it has raised $17 million in Series A financing co-led by Pappas Ventures and ProQuest Investments. Also participating in this financing round is Mustang Ventures, a China-focused venture firm.
LEAD Therapeutics raises $17 million in Series A financing
Panacos announces greater than 1 Log10 mean reduction in 300 mg bevirimat cohort
Panacos Pharmaceuticals, Inc. (NASDAQ:PANC), a biotechnology company dedicated to developing the next generation of antiviral therapeutic products, today announced preliminary results from the 300 mg cohort of a Phase 2b study of bevirimat (PA-457) in patients failing HIV therapy due to drug resistance. In this cohort, eight patients received 300 mg of bevirimat solution once daily and two patients received placebo for 14 days on top of their failing background regimen.
Anthera announces positive Phase II clinical results from A-002 cardiovascular disease trial
Anthera Pharmaceuticals, Inc., a privately-held biopharmaceutical company, reported results of a Phase II clinical trial of its first compound, A- 002, for the treatment of cardiovascular disease. The trial results suggest that treatment with A- 002 resulted in significant reductions in blood levels of total cholesterol, Non-High Density Lipoprotein Cholesterol (non HDL-C), and Low Density Lipoprotein Cholesterol (LDL-C), known as “bad” cholesterol, coupled with equally meaningful reductions of C-Reactive Protein (CRP), a recognized marker of inflammation and cardiovascular risk. Decreases in these levels with A- 002 treatment were most significant among patients already on a background of statin therapy.
Dynogen announces the presentation of its positive Phase 1b trial results at the American College of Gastroenterology Annual Scientific Meeting (ACG) in Philadelphia, PA
Dynogen Pharmaceuticals, Inc. announced the presentation of its positive Phase 1b trial results for its DDP733 (pumosetrag) nocturnal gastroesophageal reflux disease (NGERD) program at the American College of Gastroenterology Annual Scientific Meeting (ACG) in Philadelphia, PA. The randomized, double-blind, placebo-controlled study demonstrated proof-of- concept and overall safety and tolerability of DDP733 in reducing reflux events. The ACG abstract was authored by researchers from the Mayo Clinic and Dynogen. The DDP733 results were presented on October 14, 2007 during a poster session.
Optherion completes $37 million start up financing
Optherion, Inc., a company developing products to diagnose and treat dry and wet Age-related Macular Degeneration (AMD) and other chronic diseases involving the alternative complement system, announced today that it has raised $37 million in start up financing.
BrainCells, Taisho Pharmaceutical, sign licensing agreement for novel CNS program
BrainCells Inc. (BCI) and Taisho Pharmaceutical Co., Ltd. (Taisho) today announced that BCI has in-licensed a novel development program from Taisho that BCI will develop for central nervous system (CNS) indications, including mood disorders. Taisho retains rights to the program in Japan and China, while BCI will have rights for the remainder of the world. Financial terms were not disclosed.
FlowCardia today announced it has raised $30 million in Series C financing
FlowCardia, Inc., a medical device company developing endovascular devices for coronary and peripheral chronic total occlusion (CTO) recanalization, today announced it has raised $30 million in Series C financing. Gilde Healthcare Partners led the financing, joined by new investors Life Sciences Partners, Hambrecht & Quist Capital Management LLC and New Science Ventures and existing investors Frazier Healthcare Ventures, JP Morgan Partners and Pappas Ventures. Rockport Venture Partners and Gold Hill Capital also participated in this round.
TargeGen initiates Phase II clinical trial of topically-applied drug for age-related macular degeneration
TargeGen, Inc. today announced that the Company has initiated a multi-center Phase II clinical trial of topically applied TG100801 in patients with age-related macular degeneration (AMD).
Athersys begins Phase I trial for ATHX-105 for treatment of obesity
Athersys, Inc., a wholly owned subsidiary of BTHC VI (OTC Bulletin Board: BVIC), announced today that it has initiated a Phase I clinical trial in the United Kingdom for ATHX-105, the company’s oral, selective 5HT2c receptor agonist for treating obesity.
TargeGen closes on $40 million venture round
TargeGen, Inc. has announced that the Company has successfully closed a $40M venture round of financing.
